Accelerating Lead Optimization in Drug Discovery
Gifford Bioscience is a UK based specialist CRO with a global customer base. Our receptor pharmacology and occupancy assays provide critical data for the lead optimization stage of your drug discovery research.
Our PhD level scientists are experts in gold-standard radiometric methods, in fluorescence detection and in label-free, kinetic affinity techniques. For our range of specialist assays, we use human and animal tissue, cultured cells, membranes, and recombinant proteins. With robust science, fast turnaround and frequent updates, our customers know their research is in the best hands.
Determination of receptor affinities and ligand binding parameters for test compounds in a tissue homogenate or cell preparation.
Measurement of second messenger levels resulting from ligand binding. Determination of potency and efficacy of compounds and identification of agonists and antagonists.
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Imaging the distribution of a labeled test drug in tissue sections. Quantification of ligand binding in regions of interest.
Kinetic, label-fee measurement of a drug’s affinity for its receptor using Surface Plasmon Resonance (SPR).
Measurement of the degree to which a test compound engages its target receptor in tissues or in an animal.
Measurement of a compounds transport into cells or efflux from cells. Determination of a compound’s potency and efficacy.
Additional Services
as part of a core receptor pharmacology study
Ancillary Services
as part of a core receptor pharmacology study
Custom Radiolabeling
Human and Animal Tissue
ELISAs
Cell Culture & Transfections
Latest News
Celebrating the International Day of Women and Girls in Science, February 11th
Three of our female scientists talk about what inspired them to a career in science. Video Link - Click Here...
ELRIG 2023 – We’re Exhibiting
Gifford Bioscience will be exhibiting at this year's ELRIG – Drug Discovery meeting in Liverpool on the 18th and...
Download Our Latest Price Guide
We have updated our price guide, adding further tables for our standard assays and new tiers for volume discounts....
Who We Are
88% recurring customers
50% from USA
25% EU
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