PamGene International B.V.
PamGene advances neuroscience by revealing functional kinase signaling in real time from limited, physiologically relevant brain and neuronal samples. The KinomPro® platform profiles over 380 kinases simultaneously from minimal lysate, uncovering active pathways and dynamic signaling events that transcriptomics and proteomics cannot capture alone.
Neuroscience teams use PamGene to:
- Map neuro-immune and neuro-inflammatory signaling programs
- Dissect mechanisms of neuronal survival, plasticity, and degeneration
- Functionally characterize CNS models and therapeutic mechanisms
- Stratify patient cohorts and uncover actionable signaling biomarkers
Applications include neuro-oncology, neurodegeneration (AD/PD), neuro-inflammation, psychiatric disorders, and CNS drug discovery.
With over 20+ years of peer-reviewed adoption and a CE-IVD ICI response predictor, PamGene empowers fundamental, translational, and clinical neuroscience programs with mechanistic depth and predictive insight.