The Ion Laboratory (or IonLab) is a shared electrophysiology service for NYU Langone investigators, as well as other academic and industry partners. The IonLab is a resource initiated by the Ion Channels and Transporters in Immunity Research Program directed by Stefan Feske, MD. Our services include a range of techniques, including patch clamping of brain slices and isolated cells, cell volume determination, measurements of intracellular Ca2+, thallium flux assays as an index of K+ channel activity, and other measurements of transporter and ion channel activity that are necessary to maintain cell health and facilitate cellular functions.