At ScaleBio, we leverage the cell as the compartment to employ combinatorial indexing single-cell profiling solutions. This method enables increased levels of sample multiplexing, increased cell throughput, and support for a broad range of single cell genomics applications. Numbers of cells or nuclei can be scaled exponentially to enable single-cell experiments with 100s of thousands to millions of cells, at a fraction of the cost of on-market single-cell isolation instruments. We currently have products to support scRNAseq, scATACseq, and are developing applications for single-cell methylation, protein, and multi-omic analysis.